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[用A2型流感病毒免疫后抗巨噬细胞、抗淋巴细胞和抗胸腺细胞血清免疫抑制作用的比较]

[Comparison of the immunodepressant effect of antimacrophage, antilymphocyte and antithymocyte sera following immunization with influenza virus A2].

作者信息

Dobrodeeva L K

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1977(1):74-8.

PMID:300205
Abstract

An immunodepressive action of the anticellular sera was cause by the competition of the serum and viral antigens, as well as by the specific influence of the sera on the corresponding cells. The antimacrophagal serum decreased the monocyte content in the peripheral blood, peritoneal exudate, and retarded the antibody formation in the lymphoid organs. The antilymphocytic serum depressed the development of the plasma cell reaction in the lymph nodes and the spleen, this being expressed in a depression of the increase of the serum antihemagglutinin titre. The antithymocytic serum shortened the period of the active antibody formation.

摘要

抗细胞血清的免疫抑制作用是由血清与病毒抗原的竞争以及血清对相应细胞的特异性影响所引起的。抗巨噬细胞血清降低了外周血、腹腔渗出液中的单核细胞含量,并延缓了淋巴器官中抗体的形成。抗淋巴细胞血清抑制了淋巴结和脾脏中浆细胞反应的发展,这表现为血清抗血凝素滴度升高的抑制。抗胸腺细胞血清缩短了活性抗体形成的时间。

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