伴有气道受压的喉气囊肿使黏膜类天疱疮病情复杂化。
Laryngoceles with airway compromise complicating mucous membrane pemphigoid.
作者信息
Wijaya Carolyn, Morgan Lucy, Novakovic Daniel, Riminton Sean
机构信息
Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.
Immunology Department, Concord Repatriation General Hospital, Concord, New South Wales, Australia.
出版信息
BMJ Case Rep. 2018 Jul 18;2018:bcr-2018-225316. doi: 10.1136/bcr-2018-225316.
Abstract
Mucous membrane pemphigoid (MMP) encompasses a group of autoantibody-mediated, subepithelial blistering diseases, which primarily affect mucosal surfaces including oral, ocular, skin, genital, nasopharyngeal and oesophageal sites. We present a first description of laryngoceles as a manifestation of mucous membrane pemphigoid resulting in dynamic airway closure. Mucosal injury at other sites had previously resulted in pathergy and localised cicatrisation. We discuss successful combined medical and transcutaneous surgical intervention designed to avoid tracheostomy and minimise iatrogenic laryngeal cicatrisation.
摘要
黏膜类天疱疮（MMP）是一组自身抗体介导的上皮下疱性疾病，主要累及包括口腔、眼部、皮肤、生殖器、鼻咽部和食管部位在内的黏膜表面。我们首次描述了喉膨出作为黏膜类天疱疮的一种表现形式，导致动态气道闭合。此前其他部位的黏膜损伤曾导致同形反应和局部瘢痕形成。我们讨论了成功的联合药物和经皮手术干预措施，旨在避免气管切开术并尽量减少医源性喉瘢痕形成。
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