Division of Cardiovascular Medicine, Sarver Heart Center (K.B., N.K.S.)
University of Arizona, Tucson. Division of Cardiology, Anschutz Medical Campus (L.A.A., S.L.D., P.K., P.N.P.).
Circ Heart Fail. 2018 Aug;11(8):e005008. doi: 10.1161/CIRCHEARTFAILURE.118.005008.
The proportion of racial/ethnic minorities receiving ventricular assist devices (VADs) has previously been less than expected. It is unclear if trends have changed since the broadening of access to insurance in 2014 and the rapid adoption of VAD technology.
Using the Interagency Registry of Mechanically Assisted Circulatory Support, we analyzed time trends by race/ethnicity for 10 795 patients (white, 67.4%; African-American, 24.8%; Hispanic, 6.3%; Asian, 1.5%) who had a VAD implanted between 2012 and 2015. Linear models were fit to the annual census-adjusted rate of VAD implantation for each racial/ethnic group, stratified by sex and age group. From 2012 to 2015, African-Americans had an increase in the census-adjusted annual rate of VAD implantation per 100 000 (0.26 [95% confidence interval, 0.17-0.34]) while other ethnic groups exhibited no significant changes (white: 0.06 [-0.03 to 0.14]; Hispanic: 0.04 [-0.05 to 0.12]; Asian: 0.04 [-0.04 to 0.13]). Stratified by sex, rates increased in both African-American men and women (<0.05), but the change in rate was highest among African-American men (men 0.37 [0.28-0.46]; women 0.16 [0.07-0.25]; interaction with sex =0.004). Stratified by age group, rates increased in African-Americans aged 40 to 69 years and Asians aged 50 to 59 years (<0.05). The observed differential change in VAD implantation rate by age group was significant among African-Americans (interaction with age, <0.01) and Asians (interaction with age, =0.02).
From 2012 to 2015, VAD implantation rates increased among African-Americans but not other racial/ethnic groups. The greatest increase in rate was observed among middle-aged African-American men, suggesting a decline in racial disparities. Further investigation is warranted to reduce disparities among women and older racial/ethnic minorities.
接受心室辅助装置 (VAD) 的少数族裔比例此前一直低于预期。目前尚不清楚自 2014 年扩大保险范围和快速采用 VAD 技术以来,趋势是否发生了变化。
我们使用机械循环支持机构间注册中心,分析了 2012 年至 2015 年间植入 VAD 的 10795 名患者(白人,67.4%;非裔美国人,24.8%;西班牙裔,6.3%;亚洲人,1.5%)的种族/族裔时间趋势。为每个种族/族裔群体的男女和年龄组分层,使用线性模型拟合 VAD 植入的年度人口普查调整率。从 2012 年到 2015 年,非裔美国人每 10 万人的 VAD 植入率每年增加 0.26(95%置信区间,0.17-0.34),而其他族裔群体的变化不明显(白人:0.06 [-0.03 至 0.14];西班牙裔:0.04 [-0.05 至 0.12];亚洲人:0.04 [-0.04 至 0.13])。按性别分层,非裔美国男女的比率都有所增加(<0.05),但非裔美国男性的变化率最高(男性 0.37 [0.28-0.46];女性 0.16 [0.07-0.25];与性别交互作用=0.004)。按年龄组分层,40 至 69 岁的非裔美国人以及 50 至 59 岁的亚洲人的比率有所增加(<0.05)。非裔美国人(与年龄的交互作用,<0.01)和亚洲人(与年龄的交互作用,=0.02)的年龄组之间观察到的 VAD 植入率的差异变化具有统计学意义。
从 2012 年到 2015 年,VAD 植入率在非裔美国人中增加,但在其他族裔中没有增加。非裔美国中年男性的比率增长最大,表明种族差异有所缩小。需要进一步调查以减少女性和老年少数族裔的差异。