Cleveland Clinic Lerner College of Medicine at Case Western Reserve University, Cleveland, OH, USA.
Division of Pediatric Cardiology, Cleveland Clinic Children's, Cleveland Clinic Lerner College of Medicine, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
Curr Cardiol Rep. 2018 Jul 18;20(9):75. doi: 10.1007/s11886-018-1015-6.
This review aims to summarize and provide an update of evidence for cardiac resynchronization therapy (CRT) in pediatric and adult congenital heart disease (CHD).
CRT is a valuable tool in the treatment of heart failure in the setting of CHD. Current evidence points toward the ability of this therapy to increase hemodynamic parameters and reduce heart failure-related symptoms. Within the CHD population, patients with systemic left ventricles appear to benefit the most from CRT. Utilization of CRT in CHD has been technically difficult due to the complexity and variety of anatomic substrates. However, lateral thoracotomies and other advances have made implantation more feasible. The most up-to-date evidence continues to support the use of CRT in the heterogeneous population of CHD with careful and individualized patient selection. Further studies are needed to evaluate the utility of CRT for specific anatomic substrates within this population.
本综述旨在总结和更新心脏再同步治疗（CRT）在儿科和成人先天性心脏病（CHD）中的证据。
CRT 是 CHD 心力衰竭治疗的有效工具。目前的证据表明，该疗法能够增加血液动力学参数并减轻心力衰竭相关症状。在 CHD 人群中，左心室系统患者似乎从 CRT 中获益最大。由于解剖结构的复杂性和多样性，CRT 在 CHD 中的应用在技术上具有一定难度。然而，侧开胸术和其他技术的进步使植入更为可行。最新证据仍然支持在仔细和个体化患者选择的基础上，将 CRT 应用于 CHD 这一异质人群。需要进一步的研究来评估 CRT 在该人群中特定解剖结构中的应用价值。
