Hariparsad D, Omar M A, Bhigjee A I, Pillay N L
S Afr Med J. 1982 Apr 24;61(17):620-1.
Serum angiotensin-converting enzyme (SACE) and Kveim-Siltzbach test results were obtained in 25 patients with clinically active sarcoidosis. Twenty of these patients had elevated SACE levels and 17 had positive Kveim-Siltzbach tests. One patient had normal SACE activity and a negative Kveim-Siltzbach test. Four of the 6 patients with a normal SACE level had a positive Kveim-Siltzbach test and 7 of the 8 patients with a negative Kveim-Siltzbach test had elevated SACE levels. These results indicate that the two tests are complementary and increase the diagnostic specificity in sarcoidosis. We conclude that the concurrent use of SACE measurement and Kveim-Siltzbach tests is of value in the diagnosis of sarcoidosis.
对25例临床活动期结节病患者进行了血清血管紧张素转换酶（SACE）检测及Kveim-Siltzbach试验。其中20例患者SACE水平升高，17例Kveim-Siltzbach试验呈阳性。1例患者SACE活性正常且Kveim-Siltzbach试验为阴性。6例SACE水平正常的患者中有4例Kveim-Siltzbach试验呈阳性，8例Kveim-Siltzbach试验阴性的患者中有7例SACE水平升高。这些结果表明这两项检查具有互补性，可提高结节病诊断的特异性。我们得出结论，同时进行SACE检测和Kveim-Siltzbach试验对结节病的诊断具有重要价值。
