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感染辛德毕斯病毒或单纯疱疹病毒的BHK细胞中糖转运增加。

Increased sugar transport in BHK cells infected with Semliki Forest virus or with herpes simplex virus.

作者信息

Gray M A, James M H, Booth J C, Pasternak C A

出版信息

Arch Virol. 1986;87(1-2):37-48. doi: 10.1007/BF01310541.

DOI:10.1007/BF01310541
PMID:3002302
Abstract

Infection of BHK cells by SFV increases the rate of uptake of [3H]MeGlc and of [3H]dGlc at approximately 2 hours p.i. Infection by HSV increases the uptake of [3H]MeGlc and [3H]dGlc at approximately 10 hours p.i.; the increased uptake is prevented by acyclovir. It is concluded that an increased sugar uptake by infected cells reflects an increased rate of transport across the plasma membrane and is the result of cellular changes caused by virus infection.

摘要

在感染后约2小时,辛德毕斯病毒(SFV)感染BHK细胞会增加[3H]甲基葡萄糖([3H]MeGlc)和[3H]葡萄糖([3H]dGlc)的摄取速率。单纯疱疹病毒(HSV)感染在感染后约10小时会增加[3H]MeGlc和[3H]dGlc的摄取;阿昔洛韦可阻止这种摄取增加。得出的结论是,被感染细胞对糖摄取的增加反映了跨质膜转运速率的提高,并且是病毒感染引起的细胞变化的结果。

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本文引用的文献

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