表面改性对L929细胞在氧化锆纳米复合材料基底上活力的影响。
Effect of Surface Modification on Viability of L929 Cells on Zirconia Nanocomposite Substrat.
作者信息
Aivazi Moluk, Fathi Mohammadhossein, Nejatidanesh Farahnaz, Mortazavi Vajihesadat, Hashemi Beni Batoul, Matinlinna Jukka Pekka
机构信息
Biomaterials Research Group, Department of Materials Engineering, Isfahan University of Technology, Isfahan, Iran.
Dental Materials Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
J Lasers Med Sci. 2018 Spring;9(2):87-91. doi: 10.15171/jlms.2018.18. Epub 2017 Mar 20.
Zirconia bioceramic can be considered for metallic replacement in dental implant applications. A proper method of surface modification may promote better osseointegration. In study evaluated viability of fibroblast cell following surface treatment. Therefore, viability L929 cells were characterized using MTT assay and scanning electron microscopy. The viability assessment determined significant differences A-Y-TZP20 without surface treatment as compared to laser surface treatment (B), laser surface treatment + hydroxyapatiteyttrium stabilized tetragonal zirconia nanocomposite coat (C) and control. This study demonstrated that L929 cells approximately proliferated and spread on A-Y-TZP20 nanocomposite disk in laser surface treatment(B), Laser surface treatment + hydroxiapatite-yttrium stabilized tetragonal zirconia nanocomposite coat (C) groups similar to control group. Laser surface treatment showed positive effect on the viability of L929 cells.
氧化锆生物陶瓷可被考虑用于牙科植入应用中的金属替代物。一种合适的表面改性方法可能会促进更好的骨整合。本研究评估了表面处理后成纤维细胞的活力。因此，使用MTT法和扫描电子显微镜对L929细胞的活力进行了表征。活力评估确定，未经表面处理的A-Y-TZP20与激光表面处理（B）、激光表面处理+羟基磷灰石钇稳定四方氧化锆纳米复合涂层（C）和对照组相比存在显著差异。本研究表明，在激光表面处理（B）、激光表面处理+羟基磷灰石钇稳定四方氧化锆纳米复合涂层（C）组中，L929细胞在A-Y-TZP20纳米复合盘上的增殖和扩散情况与对照组相似。激光表面处理对L929细胞的活力显示出积极影响。
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