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[肺神经内分泌肿瘤的诊断与治疗]

[Diagnosis and treatment of the neuroendocrine tumors of the lung].

作者信息

Gálffy Gabriella

机构信息

Tüdõgyógyintézet, Törökbálint, Hungary.

出版信息

Magy Onkol. 2018 Jul 20;62(2):113-118. Epub 2018 Apr 12.

Abstract

Lung neuroendocrine tumors comprise 20% of all pulmonary tumors. Their appearance and behavior are very heterogeneous. Histologically they are divided into four groups, well-differentiated and low-malignant typical carcinoid, poorly differentiated and worse prognosis atypical carcinoid, and highly malignant small cell neuroendocrine carcinoma and large cell neuroendocrine carcinoma. Of these, the most common is small cell lung cancer with an incidence of 15%, while those of large cell neuroendocrine tumors and lung carcinoids are 3% and 2%, respectively. The treatment and prognosis of carcinoids are very different from those of highly malignant small cell and large cell neuroendocrine carcinomas. The paper summarizes the characteristics of lung neuroendocrine tumors.

摘要

肺神经内分泌肿瘤占所有肺部肿瘤的20%。它们的外观和行为非常异质性。组织学上它们分为四组,分化良好且恶性程度低的典型类癌、分化差且预后较差的非典型类癌,以及高恶性的小细胞神经内分泌癌和大细胞神经内分泌癌。其中,最常见的是小细胞肺癌,发病率为15%,而大细胞神经内分泌肿瘤和肺类癌的发病率分别为3%和2%。类癌的治疗和预后与高恶性的小细胞和大细胞神经内分泌癌非常不同。本文总结了肺神经内分泌肿瘤的特征。

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