Dedemadi Georgia, Takano Shota
Surgeon in the Department of Functional Anorectal Disorders at Coloproctology Center Takano Hospital in Kumamoto City, Japan, and a Surgeon in the Department of Surgery at Sismanoglio-Amalia Fleming Hospital in Athens, Greece.
Surgeon in the Department of Functional Anorectal Disorders at Coloproctology Center Takano Hospital in Kumamoto City, Japan.
Perm J. 2018;22:17-231. doi: 10.7812/TPP/17-231.
Posterior tibial nerve stimulation is a new second-line treatment for refractory fecal incontinence.
To assess the efficacy of bilateral transcutaneous posterior tibial nerve stimulation (BTPTNS) for treatment of fecal incontinence in Japanese patients and its impact on quality of life.
A prospective observational-interventional study was conducted from May 2015 to June 2017 in patients with fecal incontinence in whom conservative treatment had failed. All patients received a 30-minute session of stimulation twice weekly for 6 consecutive weeks. Evaluation at baseline and at 6 weeks involved the Wexner score, Fecal Incontinence Quality of Life (FIQL) questionnaire, and anal manometry. Patients recorded episodes of incontinence in a weekly diary.
Reduction of 50% or greater in incontinence episodes, decreased Wexner score, and improved FIQL scores.
Twenty-two patients with a median age of 64.1 years (range, 26-81 years) and men:women ratio of 9:13 completed BTPTNS. Mean episodes of fecal incontinence were significantly reduced from 4.7 to 1.5 (p < 0.05). An improvement of 50% or better in episodes of fecal incontinence was achieved in 77.2% of patients. The median Wexner score significantly decreased from 10.2 to 6.9 (p < 0.05). The median FIQL score improved from 2.7 to 3.1 (p = 0.06), and significant improvement was seen in the embarrassment domain (2.2 vs 2.8, p < 0.05). Resting and squeezing anal pressures revealed no significant changes.
Our findings suggest that BTPTNS is safe and well tolerated and may improve symptoms of fecal incontinence. This technique offers an additional noninvasive, less expensive form of treatment.
胫后神经刺激是治疗难治性大便失禁的一种新型二线治疗方法。
评估双侧经皮胫后神经刺激(BTPTNS)对日本大便失禁患者的治疗效果及其对生活质量的影响。
2015年5月至2017年6月,对保守治疗失败的大便失禁患者进行了一项前瞻性观察性干预研究。所有患者每周接受两次30分钟的刺激,连续6周。在基线和6周时进行评估,包括韦克斯纳评分、大便失禁生活质量(FIQL)问卷和肛门测压。患者在每周的日记中记录失禁发作情况。
失禁发作次数减少50%或更多、韦克斯纳评分降低、FIQL评分改善。
22例患者完成了BTPTNS,中位年龄为64.1岁(范围26 - 81岁),男女比例为9:13。大便失禁的平均发作次数从4.7次显著减少至1.5次(p < 0.05)。77.2%的患者大便失禁发作次数改善了50%或更好。中位韦克斯纳评分从10.2显著降至6.9(p < 0.05)。中位FIQL评分从2.7提高到3.1(p = 0.06),尴尬领域有显著改善(2.2对2.8,p < 0.05)。静息和收缩肛门压力无显著变化。
我们的研究结果表明,BTPTNS安全且耐受性良好,可能改善大便失禁症状。该技术提供了另一种非侵入性、成本较低的治疗方式。