College of Science , China Agricultural University , Beijing 100193 , P R China.
Institute of Inorganic and Analytical Chemistry , Johannes Gutenberg University of Mainz , Duesbergweg 10-14 , 55128 Mainz , Germany.
J Agric Food Chem. 2018 Aug 15;66(32):8489-8495. doi: 10.1021/acs.jafc.8b02056. Epub 2018 Aug 1.
A reliable analytical method for the simultaneous determination of famoxadone and oxathiapiprolin dissipation kinetics as well as the metabolites of oxathiapiprolin (IN-E8S72 and IN-WR791) in tomato and soil was developed. We studied the dissipation of famoxadone and oxathiapiprolin in tomatoes grown using different kinetic curves in the area of Beijing in 2015 and 2016. Our results show that the most suitable model for two fungicides in 2015 and 2016 was first-order kinetic and second-order kinetic with the half-lives of 3.4 to 5.2 and 2.4 to 3.0 days, respectively. In addition, we applied the dynamic plant uptake model dynamiCROP and combined it with results from the field experiments to investigate the uptake and translocation of famoxadone and oxathiapiprolin in the soil-tomato environment. Modeled and measured results of two years fitted well with R values ranging from 0.8072 to 0.9221. The fractions of famoxadone and oxathiapiprolin applied during tomato cultivation that are eventually ingested by humans via residues in crop harvest were finally evaluated and found to be in the range of one part per thousand, that is one gram intake per kilogram applied.
建立了一种同时测定二甲酰亚胺类杀菌剂肟菌酯和噻唑酰胺类杀菌剂噻唑吡普在番茄和土壤中消解动态以及噻唑吡普代谢物（IN-E8S72 和 IN-WR791）的分析方法。本文以北京地区 2015 年和 2016 年田间试验为研究对象，采用不同动力学模型对肟菌酯和噻唑吡普在番茄中的消解动态进行了研究。结果表明，两种药剂在 2015 年和 2016 年最适的动力学模型均为一级和二级动力学，半衰期分别为 3.45.2 和 2.43.0 d。此外，本文应用动态作物吸收模型 dynamiCROP，结合田间试验结果，研究了二甲酰亚胺类杀菌剂肟菌酯和噻唑酰胺类杀菌剂噻唑吡普在土壤-番茄环境中的吸收和迁移。两年的模拟和实测结果与 R 值（0.8072~0.9221）拟合良好。最终评估了番茄种植过程中施用于土壤的肟菌酯和噻唑吡普经作物收获后残留在作物中的部分最终被人类摄入的情况，发现其摄入量占施用量的千分之一，即摄入 1 克就相当于施用量 1000 克。
