Porterfield J S
Immunol Lett. 1985;11(3-4):213-7. doi: 10.1016/0165-2478(85)90170-1.
Antiviral antibody can promote viral entry into macrophages by pathways involving cellular receptors for the Fc portion of immunoglobulin or for complement components. Whether virus taken up through these routes is restricted or results in productive infection depends upon a balance between a number of variables. These include the virus strain and dose, the macrophage source and state of activation, the concentration, class and viral specificity of the antibody, and environmental factors such as time and temperature. Under appropriate conditions viral replication can be enhanced by antiviral antibodies.
抗病毒抗体可通过涉及免疫球蛋白Fc部分或补体成分细胞受体的途径促进病毒进入巨噬细胞。通过这些途径摄取的病毒是受到限制还是导致 productive 感染取决于多种变量之间的平衡。这些变量包括病毒株和剂量、巨噬细胞来源和激活状态、抗体的浓度、类别和病毒特异性，以及时间和温度等环境因素。在适当条件下，抗病毒抗体可增强病毒复制。
