Hayashi M, Tsuda H, Okumura M, Hirose M, Ito N
J Comp Pathol. 1986 Jan;96(1):35-46. doi: 10.1016/0021-9975(86)90021-6.
A histological classification of 74 nephroblastomas found in slaughtered swine is reported. The tumours were classified into 4 main types; nephroblastic (29 cases); epithelial (38 cases); mesenchymal (one case), and miscellaneous (6 cases), on the basis of their histological characteristics and especially on their relative contents of epithelial and mesenchymal elements. The nephroblastic type was further divided into 3 subtypes: nephroblastic only (one case), nephroblastic predominance 13 cases) and nephroblastic equal to epithelial (15 cases). Similarly, the epithelial type was classified into two subtypes: epithelial only (one case) and epithelial predominance (37 cases). The histological features of these tumours were compared with those of human nephroblastoma. The classification of swine nephroblastomas made in this study closely resembles that of human tumours. Two examples of the nephroblastic type were metastasized but none of the other types.
报告了对屠宰猪中发现的74例肾母细胞瘤的组织学分类。根据肿瘤的组织学特征，特别是上皮和间充质成分的相对含量，将肿瘤分为4种主要类型：肾母细胞型（29例）；上皮型（38例）；间充质型（1例）和混合型（6例）。肾母细胞型进一步分为3个亚型：单纯肾母细胞型（1例）、肾母细胞为主型（13例）和肾母细胞与上皮相等型（15例）。同样，上皮型分为两个亚型：单纯上皮型（1例）和上皮为主型（37例）。将这些肿瘤的组织学特征与人类肾母细胞瘤的特征进行了比较。本研究中对猪肾母细胞瘤的分类与人类肿瘤的分类非常相似。肾母细胞型有2例发生转移，其他类型均未发生转移。
