Hollis P H, Malis L I, Zappulla R A
J Neurosurg. 1986 Feb;64(2):253-6. doi: 10.3171/jns.1986.64.2.0253.
The risk of neurological deterioration after removal of cerebrospinal fluid below the level of a complete spinal subarachnoid block is generally accepted. The actual incidence of deterioration after lumbar puncture in the presence of a complete block remains unknown. The present retrospective case analysis includes a review of 100 patients found to have complete block on myelography: 50 cases with a lumbar puncture and 50 cases with a C1-2 puncture. Each group consisted of a similar age range, neurological status prior to myelography, level of block, and nature of disease. Seven patients (14%) had significant neurological deterioration after lumbar puncture, while no deterioration was seen after a C1-2 puncture. A summary of those cases in which deterioration followed lumbar puncture is presented and the possible pathophysiology is discussed. From this analysis, the estimated risk of downward spinal coning after lumbar puncture below a complete spinal subarachnoid block caused by a mass lesion is at least 14%.
在完全性脊髓蛛网膜下腔阻滞平面以下抽取脑脊液后发生神经功能恶化的风险已得到普遍认可。在存在完全性阻滞的情况下,腰椎穿刺后神经功能恶化的实际发生率尚不清楚。本回顾性病例分析包括对100例经脊髓造影发现存在完全性阻滞的患者的回顾:50例行腰椎穿刺,50例行C1 - 2穿刺。每组患者的年龄范围、脊髓造影前的神经状态、阻滞平面和疾病性质相似。7例(14%)患者在腰椎穿刺后出现明显的神经功能恶化,而C1 - 2穿刺后未见恶化。本文呈现了腰椎穿刺后出现恶化的病例总结,并讨论了可能的病理生理学机制。通过该分析,由占位性病变导致的完全性脊髓蛛网膜下腔阻滞以下行腰椎穿刺后发生脊髓向下圆锥化的估计风险至少为14%。