Jooma R, Hayward R D
J Neurol Neurosurg Psychiatry. 1984 Apr;47(4):386-90. doi: 10.1136/jnnp.47.4.386.
Neurological deterioration sometimes follows removal of cerebro-spinal fluid by lumbar puncture below a spinal block caused by a tumour. Experience has shown that similar impaction of a spinal intradural tumour may occur following the draining of hydrocephalus. We have used the term "upward spinal coning " to describe this and report four cases in which impaction of an intradural metastasis occurred when the obstructive hydrocephalus caused by the primary intracranial tumour was relieved. The possible mechanisms are discussed. Awareness of the syndrome is important for early diagnosis and treatment and motor power should be assessed regularly following the relief of hydrocephalus caused by a tumour known to seed in the spinal subarachnoid space.
在因肿瘤导致脊髓阻滞以下行腰椎穿刺抽取脑脊液后，有时会出现神经功能恶化。经验表明，在脑积水引流后，脊髓硬膜内肿瘤也可能发生类似的压迫情况。我们使用“脊髓向上压迫”这一术语来描述这种情况，并报告了4例因原发性颅内肿瘤引起的梗阻性脑积水缓解后发生硬膜内转移瘤压迫的病例。文中讨论了可能的机制。认识到该综合征对于早期诊断和治疗很重要，对于已知会在脊髓蛛网膜下腔播散的肿瘤引起的脑积水缓解后，应定期评估运动能力。
