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前锯肌平面阻滞用于微创直接冠状动脉旁路移植术与更高阿片类药物消耗量的关联:一项回顾性观察研究。

Association of Serratus Anterior Plane Block for Minimally Invasive Direct Coronary Artery Bypass Surgery With Higher Opioid Consumption: A Retrospective Observational Study.

作者信息

Moll Vanessa, Maffeo Carla, Mitchell Matthew, Ward Ceressa T, Groff Robert F, Lee Simon C, Halkos Michael E, Jabaley Craig S, O'Reilly-Shah Vikas N

机构信息

Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA.

Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA.

出版信息

J Cardiothorac Vasc Anesth. 2018 Dec;32(6):2570-2577. doi: 10.1053/j.jvca.2018.04.043. Epub 2018 Apr 26.

DOI:10.1053/j.jvca.2018.04.043
PMID:30037575
Abstract

OBJECTIVE

The optimal regional technique for minimally invasive direct coronary artery bypass (MIDCAB) has yet to be determined. The aim of this study was to compare the efficacy of ultrasound-guided serratus anterior plane block (SAPB) with paravertebral block (PVB) and no block for controlling acute thoracotomy pain after robotic-assisted coronary artery bypass grafting (CABG).

DESIGN

This is a retrospective study. Multiple variable regression analyses were performed.

SETTING

The study was performed as a single institution.

PARTICIPANTS

All patients underwent robotic-assisted CABG.

INTERVENTION

Data were analyzed from 197 patients during a 27-month period. Charts were abstracted manually to ascertain type of nerve block, age, gender, use of home opioids, use of adjuncts for opioid reduction, Society of Thoracic Surgeons predicted long length of stay (LOS), total opioid consumption during the 72 hours after surgery, and postoperative LOS. The authors' primary outcome was total morphine equivalents consumed during the first 72 hours after surgery. The secondary outcome was hospital LOS.

MEASUREMENTS AND MAIN RESULTS

Patients who received SAPB did not have significantly different opioid consumption than patients who had no block (p = 0.15), but it was increased significantly compared to patients administered PVB (PVB v SAPB catheter, p = 0.049; PVB v SAPB single shot, p = 0.049). There were no significant differences between groups in terms of postoperative LOS.

CONCLUSION

These findings suggest SAPB might not cover adequately the incisional and tube pain associated with MIDCAB. If validated by prospective studies, these findings suggest that SAPB should be considered only for patients who are not candidates for PVB.

摘要

目的

微创直接冠状动脉旁路移植术(MIDCAB)的最佳区域技术尚未确定。本研究的目的是比较超声引导下前锯肌平面阻滞(SAPB)与椎旁阻滞(PVB)以及不进行阻滞在机器人辅助冠状动脉旁路移植术(CABG)后控制急性开胸疼痛的疗效。

设计

这是一项回顾性研究。进行了多变量回归分析。

设置

该研究在单一机构进行。

参与者

所有患者均接受机器人辅助CABG。

干预措施

分析了27个月期间197例患者的数据。通过人工提取图表以确定神经阻滞类型、年龄、性别、家庭阿片类药物的使用、减少阿片类药物使用的辅助药物、胸外科医师协会预测的长住院时间(LOS)、术后72小时内的总阿片类药物消耗量以及术后LOS。作者的主要结局是术后前72小时内消耗的吗啡当量总量。次要结局是住院LOS。

测量与主要结果

接受SAPB的患者与未进行阻滞的患者相比,阿片类药物消耗量无显著差异(p = 0.15),但与接受PVB的患者相比显著增加(PVB与SAPB导管,p = 0.049;PVB与SAPB单次注射,p = 0.049)。各组之间术后LOS无显著差异。

结论

这些发现表明,SAPB可能无法充分覆盖与MIDCAB相关的切口和置管疼痛。如果前瞻性研究证实这些发现,则表明仅对于不适合PVB的患者才应考虑使用SAPB。

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