Garner Orlando, Iardino Alfredo, Ramirez Ana, Yakoby Maty
Internal Medicine, Texas Tech University Health Science Center at the Permian Basin, Odessa, Texas, USA.
BMJ Case Rep. 2018 Jul 23;2018:bcr-2017-223891. doi: 10.1136/bcr-2017-223891.
Bodybuilders use anabolic-androgenic steroids to increase muscle mass, but abuse of these hormones has been related to cardiomyopathy in the past. A 60-year-old Caucasian male bodybuilder with medical history of male hypogonadism and on testosterone replacement therapy, allegedly preparing for a weightlifting competition and receiving stem cell infusions from his trainer, is transferred to the intensive care unit for worsening shortness of breath after failing treatment for community-acquired pneumonia. Chest X-ray on transfer was suggestive of pulmonary oedema, and transthoracic echocardiography showed an ejection fraction of 25%-30%. The patient was taken for cardiac catheterisation, which yielded non-ischaemic cardiomyopathy. His testosterone levels were supratherapeutic. Anabolic-androgenic steroid abuse can be a cause of cardiomyopathy in patients who have no other risk factor for such disease.
健美运动员使用合成代谢雄激素类固醇来增加肌肉量,但过去滥用这些激素与心肌病有关。一名60岁的白人男性健美运动员,有男性性腺功能减退病史且正在接受睾酮替代治疗,据称他正在为一场举重比赛做准备,并从他的教练那里接受干细胞输注,在社区获得性肺炎治疗失败后,因呼吸急促加重被转入重症监护病房。转院时的胸部X光片提示肺水肿,经胸超声心动图显示射血分数为25%-30%。患者接受了心导管检查,结果显示为非缺血性心肌病。他的睾酮水平高于治疗剂量。在没有其他此类疾病风险因素的患者中,滥用合成代谢雄激素类固醇可能是心肌病的一个病因。