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耳蜗频率调谐与耳声发射。

Cochlear Frequency Tuning and Otoacoustic Emissions.

机构信息

Caruso Department of Otolaryngology and Department of Physics and Astronomy, University of Southern California, Los Angeles, California 90033.

Caruso Department of Otolaryngology, University of Southern California, Los Angeles, California 90033.

出版信息

Cold Spring Harb Perspect Med. 2019 Feb 1;9(2):a033498. doi: 10.1101/cshperspect.a033498.

DOI:10.1101/cshperspect.a033498
PMID:30037987
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6360871/
Abstract

Otoacoustic emissions (OAEs) evoked from the inner ear are the barely audible, signature byproduct of the delicate hydromechanical amplifier that evolved within its bony walls. Compared to the sounds evoked from the ears of common laboratory animals, OAEs from human ears have exceptionally long delays, typically exceeding those of cats, guinea pigs, and chinchillas by a factor of two to three. This review asks "Why are human OAE delays so long?" and recounts efforts to locate answers in the characteristics of mechanical frequency selectivity in the inner ear. The road to understanding species differences in OAE delay leads to the identification of new invariances and to the emergence of new questions.

摘要

耳声发射(OAE)是内耳产生的几乎听不见的精细水力学放大的特征副产品。与常见实验动物耳朵产生的声音相比,人类耳朵产生的 OAE 具有异常长的延迟,通常比猫、豚鼠和龙猫的延迟长两倍到三倍。这篇综述提出了“为什么人类 OAE 延迟这么长?”的问题,并回顾了在内耳机械频率选择性特征中寻找答案的努力。了解 OAE 延迟的物种差异的途径导致了新不变性的发现,并提出了新的问题。

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本文引用的文献

1
Tectorial Membrane Traveling Waves Underlie Sharp Auditory Tuning in Humans.盖膜行波是人类敏锐听觉调谐的基础。
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Cytoarchitecture of the mouse organ of corti from base to apex, determined using in situ two-photon imaging.使用原位双光子成像确定的从基部到顶端的小鼠柯蒂氏器的细胞结构。
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Estimating cochlear frequency selectivity with stimulus-frequency otoacoustic emissions in chinchillas.利用灰鼠的刺激频率耳声发射估计耳蜗频率选择性
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Effects of low-frequency biasing on otoacoustic and neural measures suggest that stimulus-frequency otoacoustic emissions originate near the peak region of the traveling wave.低频偏置对耳声发射和神经测量的影响表明,刺激频率耳声发射起源于行波的峰值区域附近。
J Assoc Res Otolaryngol. 2012 Feb;13(1):17-28. doi: 10.1007/s10162-011-0296-x. Epub 2011 Oct 15.
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Frequency selectivity in Old-World monkeys corroborates sharp cochlear tuning in humans.旧大陆猴的频率选择性证实了人类耳蜗调谐的尖锐性。
Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17516-20. doi: 10.1073/pnas.1105867108. Epub 2011 Oct 10.
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Feed-forward and feed-backward amplification model from cochlear cytoarchitecture: an interspecies comparison.从耳蜗细胞构筑学角度看前馈和反馈放大模型:种间比较。
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Tectorial membrane travelling waves underlie abnormal hearing in Tectb mutant mice.盖膜行波异常是 Tectb 突变小鼠听力异常的基础。
Nat Commun. 2010 Oct 19;1(7):96. doi: 10.1038/ncomms1094.
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Otoacoustic estimation of cochlear tuning: validation in the chinchilla.耳蜗调谐的耳声发射估计:在南美栗鼠中的验证。
J Assoc Res Otolaryngol. 2010 Sep;11(3):343-65. doi: 10.1007/s10162-010-0217-4. Epub 2010 May 4.
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