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[急性多发性神经根神经炎患者血液和脑脊液中的淋巴细胞亚群。应用单克隆抗体对14例患者的研究]

[Lymphocyte subpopulations of the blood and cerebrospinal fluid in acute polyradiculoneuritis. Study of 14 cases using monoclonal antibodies].

作者信息

Antoine J C, Michel D, Lepetit J C, Touraine F, Laurent B, Schott B

出版信息

Rev Neurol (Paris). 1985;141(11):740-3.

PMID:3003873
Abstract

The T lymphocytes in blood and CSF of 14 patients with acute polyradiculoneuritis were studied using the OKT series of monoclonal antibodies. Results were compared with findings in two control groups. Three patients with cytomegalovirus infection showed elevation of circulating OKT 8. A significant increase in the mean ratio OKT 4/OKT 8 was noted in all other cases, corresponding in 4 of the 11 patients to a reduction in number of OKT 8 lymphocytes. The CSF was normal in 3 of the 14 cases.

摘要

使用OKT系列单克隆抗体对14例急性多发性神经根神经炎患者血液和脑脊液中的T淋巴细胞进行了研究。将结果与两个对照组的发现进行了比较。3例巨细胞病毒感染患者循环中的OKT 8升高。在所有其他病例中,OKT 4/OKT 8的平均比值显著增加,11例患者中有4例对应的OKT 8淋巴细胞数量减少。14例患者中有3例脑脊液正常。

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