Srbovan D, Mihailović J, Nikoletić K, Matovina E, Šolajić N
Department of Nuclear Medicine, Institute of Oncology Vojvodina, Sremska Kamenica, Serbia.
Clinic of Operative Oncology - Department of Patohystology and Cytology Diagnostic, Institute of Oncology Vojvodina, Sremska Kamenica, Serbia.
J Belg Soc Radiol. 2015 Sep 15;99(1):76-78. doi: 10.5334/jbr-btr.855.
A 62-year-old woman had the incidental finding of malignant struma ovarii following surgery for primary endometrial carcinoma. The patient had vaginal bleeding for one year. After gynecological examination, she was referred for fractional curettage which revealed endometrial cancer. The patient underwent total hysterectomy and bilateral adnexectomy. Histological findings of uterus confirm the presence of endometrial cancer. The left ovary showed the presence of mature teratoma with dominant thyroid tissue and focus of papillary carcinoma. Postoperatively she underwent radiation therapy and 3 months later total thyroidectomy. The stimulated thyroglobulin level was detectable. She was referred for radioiodine ablation with a dose of 3,7GBq 131-J. Post therapy scintigraphy shows pathological uptake of 131-J only in the neck. The patient continued treatment of endometrial cancer (external beam therapy). She is currently on suppressive hormone L-thyroxin therapy. Two months later hormonal status, thyroglobulin and antithyroglobulin antibodies showed optimal range.
一名62岁女性在接受原发性子宫内膜癌手术后意外发现恶性卵巢甲状腺肿。患者有一年的阴道出血症状。经过妇科检查后，她被转诊进行分段刮宫，结果显示为子宫内膜癌。患者接受了全子宫切除术和双侧附件切除术。子宫的组织学检查结果证实存在子宫内膜癌。左侧卵巢显示存在成熟畸胎瘤，其中有占主导地位的甲状腺组织和乳头状癌灶。术后她接受了放射治疗，3个月后进行了全甲状腺切除术。刺激后的甲状腺球蛋白水平可检测到。她被转诊接受剂量为3.7GBq的131-J放射性碘消融治疗。治疗后闪烁扫描显示131-J仅在颈部有病理摄取。患者继续接受子宫内膜癌治疗（外照射治疗）。她目前正在接受抑制性激素左旋甲状腺素治疗。两个月后，激素状态、甲状腺球蛋白和抗甲状腺球蛋白抗体显示在最佳范围内。
