Krishnamurthy Arvind, Ramshankar Vijayalakshmi, Vaidyalingam Venkatesh, Majhi Urmila
Department of Surgical Oncology, Cancer Institute, Womans India Association, Chennai, Tamil Nadu, India.
Department of Preventive Oncology, Cancer Institute, Womans India Association, Chennai, Tamil Nadu, India.
Indian J Nucl Med. 2013 Oct;28(4):243-5. doi: 10.4103/0972-3919.121975.
Struma ovarii (SO) is a rare form of ovarian tumor, which is defined by the presence of thyroid tissue comprising more than 50% of the overall tumor volume. The vast majority of the variants of SO are benign; however, malignant tumors have been reported in a small percentage of cases. An aggressive multimodality approach using ovarian cancer staging laparotomy, total thyroidectomy along with radioactive iodine-131 ablation, and thyroxin suppression therapy has been shown to safely treat malignant SO both its initial presentation as well as in the event of any subsequent recurrence with excellent efficacy and possibly better oncological outcomes. The rarity of the disease and the lack of evidence surrounding its management and prognosis continue to remain a challenge to the treating clinician. We present a unique case of malignant SO with an incidental synchronous association of follicular variant of papillary carcinoma of the cervical thyroid gland, this is possibly the second case reported in the English language literature.
卵巢甲状腺肿（SO）是一种罕见的卵巢肿瘤形式，其定义为甲状腺组织占肿瘤总体积的50%以上。绝大多数SO变体是良性的；然而，一小部分病例报告有恶性肿瘤。采用卵巢癌分期剖腹术、全甲状腺切除术加放射性碘-131消融以及甲状腺素抑制疗法的积极多模式方法已被证明可安全治疗恶性SO，无论是其初次表现还是随后任何复发情况，疗效极佳，可能获得更好的肿瘤学结果。该疾病的罕见性以及围绕其治疗和预后的证据不足仍然是治疗临床医生面临的挑战。我们报告了一例独特的恶性SO病例，同时偶然伴有宫颈甲状腺乳头状癌滤泡变体，这可能是英文文献中报道的第二例。
