Iakubovskiĭ S M, Gatsko G G
Vopr Med Khim. 1985 Nov-Dec;31(6):63-4.
Vmax of 5'-nucleotidase was found to be similar in liver plasmatic membranes of both 4-5 months old male rats and 24-26 months old animals. At the same time, Km value was higher in the membranes of old rats than in young animals. Insulin (administered at a dose of 2 un per 100 g of body mass) increased the enzyme Vmax without some age-dependent differences and decreased Km value in old animals as compared with controls.
发现4 - 5月龄雄性大鼠和24 - 26月龄动物的肝脏质膜中5'-核苷酸酶的最大反应速度（Vmax）相似。同时，老年大鼠膜中的米氏常数（Km）值高于年轻动物。胰岛素（以每100克体重2单位的剂量给药）增加了酶的Vmax，且无年龄依赖性差异，与对照组相比，老年动物的Km值降低。
