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[单纯疱疹病毒2型感染。病因、临床症状、诊断、治疗、HSV-2与宫颈癌]

[Herpes simplex virus type 2 infection. Etiology, clinical aspects, diagnosis, therapy, HSV-2 and cervix cancer].

作者信息

Kunkel M, Oberender H

出版信息

Zentralbl Gynakol. 1985;107(24):1473-8.

PMID:3004067
Abstract

The genital herpes infection is mostly caused by HSV-2. The analysis of epidemic data supports the common impression that herpes genitalis markedly increased. The HSV-2 is with few exceptions a sexually transmitted virus, the infectionsity is about 80%. The primary infection with HSV-2 occurs in the youth. HSV-2 survives in a latent stage in the human body for life and causes as a rule to recurrent diseases. The clinical picture is variable. The most severe complication is the sepsis of newborn. The virological diagnosis is made by isolation of virus. The therapy of herpes genitalis is problematic. It is proposed that the HSV-2 plays a key role as an initiating factor in the development of human genital cancer.

摘要

生殖器疱疹感染大多由单纯疱疹病毒2型(HSV - 2)引起。流行数据分析支持生殖器疱疹明显增多这一普遍印象。HSV - 2几乎无一例外是一种性传播病毒,感染率约为80%。HSV - 2的初次感染发生在青年时期。HSV - 2在人体内潜伏终生,并通常引发复发性疾病。临床表现多样。最严重的并发症是新生儿败血症。病毒学诊断通过病毒分离进行。生殖器疱疹的治疗存在问题。有人提出HSV - 2在人类生殖器癌的发生发展中作为起始因素起关键作用。

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