Kasová V, Trmal J, Trmalová Z, Brůcková M, Sefcovicová L
Zentralbl Bakteriol Mikrobiol Hyg A. 1985 Nov;260(3):387-95. doi: 10.1016/s0176-6724(85)80027-4.
Two cases of polyradiculoneuritis in children were noted during January, 1984. Each girl was a member of a different group of children: the first group was newly constituted of children from various remote regions of Czechoslovakia in a Medical Institution, the second one included children attending the same nursery school for a long time. In both groups, all or most of the children went through one or two respiratory infections which preceded the development of a paralytic disease. From the first girl, coxsackievirus A9 was recovered in nasopharyngeal swabs and in a stool sample. Among contacts in the Children's Medical Institution, a concurrent circulation of this enterovirus and of an adenovirus type 3 was demonstrated by isolation attempts and confirmed by serological examinations. From the second girl, coxsackie A9 and an adenovirus type 29 were demonstrated in the same stool sample and a simultaneous circulation of both virus species among the nursery school and family contacts was proved by isolation attempts and by serological investigations. The concurrent, overlapping or sequential circulation of adenoviruses and enteroviruses may perhaps contribute to a compromised immunity resulting in a manifestation of paralysis.
1984年1月记录了两例儿童多发性神经根神经炎病例。每个女孩都来自不同的儿童群体：第一组是由来自捷克斯洛伐克各个偏远地区的儿童在一家医疗机构新组成的，第二组包括长期在同一幼儿园上学的儿童。在这两组中，所有或大多数儿童在麻痹性疾病发作之前都经历了一两次呼吸道感染。从第一个女孩的鼻咽拭子和粪便样本中分离出柯萨奇病毒A9。在儿童医疗机构的接触者中，通过分离尝试证明了这种肠道病毒和3型腺病毒同时流行，并通过血清学检查得到证实。从第二个女孩的粪便样本中检测出柯萨奇A9和29型腺病毒，通过分离尝试和血清学调查证明这两种病毒在幼儿园和家庭接触者中同时流行。腺病毒和肠道病毒同时、重叠或相继流行可能会导致免疫功能受损，从而引发麻痹症状。
