Richmond S J, Caul E O, Dunn S M, Ashley C R, Clarke S K, Seymour N R
Lancet. 1979 Jun 2;1(8127):1178-81. doi: 10.1016/s0140-6736(79)91853-1.
During October and November, 1978, gastroenteritis developed in 17 of 24 young children aged between eight months and two years from an R.A.F. station in the U.K. The illness, in which diarrhoea was always the predominant symptom, had an incubation period of eight to ten days and lasted about a week. It seemed to be transmitted from child to child, and in all but one instance parents and older siblings remained well. Stool specimens from 14 of the affected children were examined bacteriologically and virologically, and a highly significant association was found between the presence of adenovirus particles in stools, identified by electron microscopy, and the acute stage of the illness. This evidence suggests that an adenovirus was the cause of this outbreak of gastroenteritis.
1978年10月至11月期间,英国皇家空军某基地24名年龄在8个月至2岁之间的幼儿中有17名患上了肠胃炎。这种疾病始终以腹泻为主要症状,潜伏期为8至10天,持续约一周。似乎是在儿童之间传播,除1例之外,患儿的父母和年长同胞均未患病。对14名患病儿童的粪便样本进行了细菌学和病毒学检查,通过电子显微镜鉴定发现,粪便中腺病毒颗粒的存在与疾病急性期之间存在高度显著的关联。这一证据表明,腺病毒是此次肠胃炎暴发的病因。