人血清中的血小板活化因子结合蛋白
Platelet-activating factor-binding protein in human serum.
作者信息
Matsumoto M, Miwa M
出版信息
Adv Prostaglandin Thromboxane Leukot Res. 1985;15:705-6.
PMID:3004155
Abstract
The occurrence of a kind of protein (PBP) with stronger PAF-binding ability than albumin was shown in human serum. The molecular weight of PBP was approximately 160K to 180K. PBP seemed to be a pentamer composed of five 32K subunits. PAF bound to PBP revealed platelet aggregation and was resistant to acetyl-hydrolase. PAF synthesized in neutrophils stimulated with the ionophore A23187 was released by PBP from cells.
摘要
在人血清中发现了一种与血小板活化因子（PAF）结合能力比白蛋白更强的蛋白质（PBP）。PBP的分子量约为160K至180K。PBP似乎是由五个32K亚基组成的五聚体。与PBP结合的PAF可导致血小板聚集，并且对乙酰水解酶具有抗性。在离子载体A23187刺激下中性粒细胞中合成的PAF可被PBP从细胞中释放出来。
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