Murakami Akari, Kamei Yoshiaki, Kusakabe Erina, Yamasawa Haruna, Aoki Reina, Komatsu Saaya, Taguchi Kana, Nishiyama Kanako, Yamashita Michiko, Sugimori Wakana, Asai Hiroaki, Mizuno Yosuke, Takada Yasutsugu
Breast Center, Ehime University Hospital.
Gan To Kagaku Ryoho. 2018 Jul;45(7):1105-1107.
We report a case of microangiopathic hemolytic anemia(MHA)caused by metastatic breast cancer treated with weekly paclitaxel. A 58-year-old woman was diagnosed with metastatic breast cancer 2 years earlier. She was treated with various chemotherapy regimens and hormonal therapy, before being switched to fulvestrant 3 months earlier. She presented with severe anemia, and was diagnosed with MHA with bone marrow carcinomatosis following bone marrow biopsy. She was treated with weekly paclitaxel and recovered successfully. A subsequent biopsy showed that the bone marrow carcinomatosis had decreased. MHA due to breast cancer is rare and is associated with poor prognosis; however, rapid initiation of chemotherapy may be effective.
