Department of Internal Medicine, Pulmonary Diseases, Critical Care, and Environmental Medicine, Tulane University Health Sciences Center, New Orleans, LA; Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Department of Pathology, Tulane University Health Sciences Center, New Orleans, LA.
Chest. 2018 Jul;154(1):e27-e30. doi: 10.1016/j.chest.2017.11.034.
A 56-year-old man with a history of common variable immunodeficiency (CVID), in addition to recurrent bronchitis and pneumonia, presented with progressively worsening shortness of breath over a period of a few months. He was able to conduct his activities of daily living at baseline; however, his condition declined over a period of months to the point of shortness of breath with climbing a flight of stairs. The patient also developed a frequent dry cough and wheezing. He denied fever, chest pain, weight loss, and hemoptysis. He had been diagnosed with CVID in 1968, at 7 years of age, after recurrent episodes of bronchitis and pneumonia, and was treated with IV immunoglobulin monthly for decades. The patient was a lifelong nonsmoker and had no significant environmental or occupational exposures. He was referred to our hospital for further management.
一位 56 岁男性，患有普通变异性免疫缺陷症（CVID），除了反复发作的支气管炎和肺炎外，还出现了几个月来逐渐加重的呼吸困难。他在基线时能够进行日常活动；然而，他的病情在几个月内恶化，以至于爬一段楼梯都会出现呼吸困难。该患者还出现了频繁的干咳和喘息。他否认发热、胸痛、体重减轻和咯血。他于 1968 年 7 岁时被诊断为 CVID，当时他反复出现支气管炎和肺炎，并接受了数十年的每月静脉注射免疫球蛋白治疗。该患者是一名终身不吸烟者，没有明显的环境或职业暴露。他被转至我院接受进一步治疗。
