Zarins B, McInerney V K
Arthroscopy. 1985;1(1):8-16. doi: 10.1016/s0749-8063(85)80072-4.
Calcium pyrophosphate deposition disease (CPDD) is a condition in which calcium pyrophosphate dihydrate crystals are deposited in joint articular cartilage, menisci, and synovium. The main clinical presentations of CPDD are chondrocalcinosis--calcification of cartilage, pseudogout--acute joint inflammation due to crystal-induced synovitis, and pyrophosphate arthropathy--degenerative joint disease similar to osteoarthritis associated with calcium pyrophosphate crystal deposition. The clinical importance of CPDD for the arthroscopist is the ability to recognize the condition so that appropriate treatment can be instituted. Arthroscopy is valuable for diagnosis as well as lavage and intraarticular debridement or meniscectomy. Tissue removed for microscopic examination should be sent to the laboratory in saline, since formalin dissolves the crystals. Postarthroscopy treatment of CPDD should include oral antiinflammatory medication. Asymptomatic chondrocalcinosis does not require treatment.
焦磷酸钙沉积病（CPDD）是一种焦磷酸二水合物晶体沉积于关节软骨、半月板和滑膜的病症。CPDD的主要临床表现为软骨钙质沉着症——软骨钙化、假性痛风——晶体诱导的滑膜炎所致的急性关节炎症，以及焦磷酸关节病——与焦磷酸钙晶体沉积相关的类似于骨关节炎的退行性关节疾病。CPDD对关节镜医师的临床重要性在于能够识别该病，以便进行适当治疗。关节镜检查对于诊断以及灌洗和关节内清创或半月板切除术很有价值。用于显微镜检查的切除组织应置于盐水中送往实验室，因为福尔马林会溶解晶体。CPDD关节镜检查后的治疗应包括口服抗炎药物。无症状的软骨钙质沉着症无需治疗。
