在用脱羧酶抑制剂预处理后，冷冻和储存方法对脑内多巴（DOPA）和5-羟色胺（5-HTP）浓度的影响。
Influence of freezing and storage methods on concentrations of brain DOPA and 5 HTP after pretreatment with a decarboxylase inhibitor.
作者信息
McNamara M C, Miller A T, Davis J N
出版信息
Res Commun Chem Pathol Pharmacol. 1977 Mar;16(3):569-72.
PMID:300489
Abstract
The concentrations of DOPA and 5 hydroxytryptophan in rat brain were decreased by freezing on dry ice rather than in liquid nitrogen, and by a 5 minute delay in removing and freezing the brain by either method. The effect of post-mortem delay in freezing was greater for 5 HTP than for DOPA.
摘要
与在液氮中冷冻相比，在干冰上冷冻，以及无论采用哪种方法移除和冷冻大脑时延迟5分钟，都会使大鼠大脑中多巴胺（DOPA）和5-羟色氨酸（5-hydroxytryptophan）的浓度降低。死后延迟冷冻对5-羟色氨酸（5-HTP）的影响比对多巴胺（DOPA）的影响更大。
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