López-de-Andrés Ana, Luis Del Barrio José, Hernández-Barrera Valentín, de Miguel-Díez Javier, Jimenez-Trujillo Isabel, Martinez-Huedo María Angeles, Jimenez-García Rodrigo
Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Rey Juan Carlos University, Alcorcón, Madrid, Spain,
Respiratory Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Diabetes Metab Syndr Obes. 2018 Jul 20;11:367-374. doi: 10.2147/DMSO.S170253. eCollection 2018.
To investigate the association between migraine and diabetes mellitus while controlling for several socio-demographic characteristics, comorbidities, and lifestyle variables. We also aimed to identify which of these variables are associated with migraine among diabetics.
We conducted a cross-sectional study using data taken from the European Health Interview Surveys for Spain conducted in 2009/10 (n=22,188) and 2014 (n=22,842). We selected those subjects ≥40 years of age. Diabetes status was self-reported. One non-diabetic control was matched by the year of survey, age, and sex for each diabetic case. The presence of migraine was defined as the affirmative answer to both of the following questions: "Have you suffered migraine or frequent headaches over the last 12 months?" and "Has your physician confirmed the diagnosis?". Independent variables included demographic and socio-economic characteristics, health status variables, lifestyle, and pain characteristics.
The prevalence of migraine was significantly higher among those suffering from diabetes (14.9% vs. 13.0%; =0.021). The multivariable analysis showed that diabetes was not associated with a higher risk of migraine (adjusted OR 1.06; 95%CI 0.89-1.25). Among diabetic subjects, female sex, suffering concomitant mental disorders, respiratory disorders, neck pain, and low back pain were variables associated with suffering from migraine.
We found no significant differences in the prevalence of migraine between diabetics and non-diabetic age- and sex-matched controls after controlling for possible confounders.
在控制多种社会人口学特征、合并症和生活方式变量的情况下，研究偏头痛与糖尿病之间的关联。我们还旨在确定这些变量中哪些与糖尿病患者的偏头痛有关。
我们进行了一项横断面研究，使用的数据来自2009/10年（n = 22188）和2014年（n = 22842）在西班牙进行的欧洲健康访谈调查。我们选择了年龄≥40岁的受试者。糖尿病状态通过自我报告获得。为每例糖尿病患者匹配一名非糖尿病对照，对照在调查年份、年龄和性别方面与之匹配。偏头痛的存在定义为对以下两个问题均给出肯定回答：“在过去12个月里，你是否患有偏头痛或频繁头痛？”以及“你的医生是否已确诊？”。自变量包括人口统计学和社会经济特征、健康状况变量、生活方式和疼痛特征。
糖尿病患者中偏头痛的患病率显著更高（14.9%对13.0%；P = 0.021）。多变量分析显示，糖尿病与偏头痛风险较高无关（调整后的比值比为1.06；95%置信区间为0.89 - 1.25）。在糖尿病患者中，女性、患有合并精神障碍、呼吸系统疾病、颈部疼痛和下背部疼痛是与患偏头痛相关的变量。
在控制可能的混杂因素后，我们发现糖尿病患者与年龄和性别匹配的非糖尿病对照在偏头痛患病率方面无显著差异。
