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[乳腺病变中ACR4微钙化的放射-组织学相关性:181例病例及文献综述]

[Radio-histological correlation of ACR4 microcalcifications in breast lesions: about 181 cases and literature review].

作者信息

Guennoun Ahmed, Krimou Yousra, Bouchikhi Chahrazed, Mamouni Nisrine, Errarhay Sanaa, Banani Abdelaziz

机构信息

Service d'Obstétrique et de Gynécologie I, Hôpital Universitaire Hassan II, Fès, Maroc.

出版信息

Pan Afr Med J. 2018 Mar 2;29:140. doi: 10.11604/pamj.2018.29.140.13699. eCollection 2018.

DOI:10.11604/pamj.2018.29.140.13699
PMID:30050604
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6057563/
Abstract

The Bi-RADS (Breast Imaging Reporting and Data System) classification developed by the ACR (American College of Radiology) is the classification system for radiological images recommended for breast cancer screening. The ACR 4 microcalcification is an indeterminate or suspected abnormality with 2-95% probability of malignancy, according to studies. This disparity pushed us to conduct this retrospective study of 181 patients in the Department of Obstetrics and Gynecology I at the Hassan II University Hospital, Fez, over a period of 5 years. This study aimed to report the histological results of breast lesions radiologically classified as ACR4 in order to assess their radio-histological correlation and to improve therapeutic approach. All patients underwent breast imaging examinations and then anatomopathologic examination was performed using different techniques. There was a clear predominance of benign lesions with a rate of 62% versus 29% of malignant lesions and only 9% were intermediate lesions. Adenofibroma was the most common histological finding (30% of cases), invasive ductal carcinoma was the most frequent malignant lesion (17% of cases). We performed a literature review which showed that our results were in line with findings of other studies, with a positive predictive value of 29%. Nevertheless, ACR classification divided into subcategories 4a, b and c should be used due to the significant number of unnecessary surgical interventions.

摘要

由美国放射学会(ACR)制定的乳腺影像报告和数据系统(Bi-RADS)分类是推荐用于乳腺癌筛查的放射影像分类系统。根据研究,ACR 4类微钙化是一种不确定或疑似异常,恶性概率为2-95%。这种差异促使我们对非斯哈桑二世大学医院第一妇产科的181例患者进行了为期5年的回顾性研究。本研究旨在报告放射学分类为ACR4的乳腺病变的组织学结果,以评估其放射学与组织学的相关性,并改进治疗方法。所有患者均接受了乳腺影像学检查,然后采用不同技术进行了病理检查。良性病变明显占优势,比例为62%,恶性病变为29%,中间性病变仅占9%。腺纤维瘤是最常见的组织学发现(占病例的30%),浸润性导管癌是最常见的恶性病变(占病例的17%)。我们进行了文献综述,结果表明我们的结果与其他研究结果一致,阳性预测值为29%。然而,由于不必要的手术干预数量众多,应使用分为4a、b和c子类的ACR分类。

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1
[Radio-histological correlation of ACR4 microcalcifications in breast lesions: about 181 cases and literature review].[乳腺病变中ACR4微钙化的放射-组织学相关性:181例病例及文献综述]
Pan Afr Med J. 2018 Mar 2;29:140. doi: 10.11604/pamj.2018.29.140.13699. eCollection 2018.
2
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Diagn Interv Radiol. 2015 May-Jun;21(3):189-94. doi: 10.5152/dir.2014.14103.

引用本文的文献

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Breast Cancer in Togolese Women: Imaging and Clinicopathological Findings.多哥女性乳腺癌:影像学与临床病理表现
Breast Cancer (Auckl). 2021 May 30;15:11782234211020242. doi: 10.1177/11782234211020242. eCollection 2021.

本文引用的文献

1
Simple rules for ultrasonographic subcategorization of BI-RADS®-US 4 breast masses.BI-RADS®-US 4 类乳腺肿块的超声亚型分类简单规则。
Eur J Radiol. 2013 Aug;82(8):1231-5. doi: 10.1016/j.ejrad.2013.02.032. Epub 2013 Mar 27.
2
Clinical outcome of breast cancer BI-RADS 4 lesions during 2003-2008 in the National Cancer Institute Thailand.泰国国家癌症研究所2003 - 2008年期间乳腺癌BI - RADS 4级病变的临床结果
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3
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Subcategorization of ultrasonographic BI-RADS category 4: positive predictive value and clinical factors affecting it.超声 BI-RADS 4 类的再分类:阳性预测值及其影响因素。
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Biopsy rate and positive predictive value for breast cancer in BI-RADS category 4 breast lesions.乳腺影像报告和数据系统(BI-RADS)4类乳腺病变中乳腺癌的活检率及阳性预测值
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Clinical implications of subcategorizing BI-RADS 4 breast lesions associated with microcalcification: a radiology-pathology correlation study.BI-RADS 4 级伴微钙化乳腺病变的亚分类的临床意义:一项放射科-病理相关性研究。
Breast J. 2010 Jan-Feb;16(1):28-31. doi: 10.1111/j.1524-4741.2009.00863.x. Epub 2009 Nov 19.