硫化氢诱导活细胞中超分子自组装。
Hydrogen sulfide induced supramolecular self-assembly in living cells.
机构信息
CAS Center for Excellence in Nanoscience, CAS Key Laboratory of Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing 100190, China.
出版信息
Chem Commun (Camb). 2018 Aug 21;54(65):9051-9054. doi: 10.1039/c8cc05174g. Epub 2018 Jul 27.
PMID:30051134
Abstract
Here we developed a critical gasotransmitter (HS) mediated reduction to induce supramolecular self-assembly in multiple living cell lines. Specifically, the reduction converted an azido group to an amine which allowed the formation of intramolecular hydrogen bonds. The hydrogen bonds planarized the assembling molecules and promoted the supramolecular self-assembly.
摘要
在这里，我们开发了一种关键的气体递质（HS）介导的还原反应，以诱导多种活细胞系中的超分子自组装。具体而言，还原反应将叠氮基团转化为胺基，从而形成分子内氢键。氢键使组装分子平面化，并促进超分子自组装。
Zotero 插件