Department of Occupational Medicine, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc, Czech Republic.
Department of Respiratory Medicine, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc, Czech Republic.
Occup Med (Lond). 2018 Sep 13;68(7):482-484. doi: 10.1093/occmed/kqy106.
Silicosis, caused by inhaling dust containing free crystalline silica, typically has a chronic course, with the numbers of silicosis patients declining globally. Much rarer are the acute and subacute forms. Presented is a case of severe subacute (accelerated) silicosis. The condition resulted from ~2 years of very intense exposure without appropriate personal protective equipment while sandblasting. The patient's initial symptoms were progressive cough, dyspnoea and weight loss. Given his occupational history, typical clinical manifestations and radiological findings, an initial diagnosis of accelerated silicosis was proposed and histologically confirmed. The patient was a candidate for lung transplantation. The case demonstrates a rare but largely preventable disease with serious health effects and a poor prognosis.
矽肺是由吸入含有游离结晶二氧化硅的粉尘引起的，通常呈慢性病程，全球矽肺患者数量正在减少。更为罕见的是急性和亚急性形式。本文报告了一例严重的亚急性（加速性）矽肺病例。该病例是由于喷砂作业期间长达 2 年的高强度暴露，且没有使用适当的个人防护设备导致。患者最初的症状为进行性咳嗽、呼吸困难和体重减轻。鉴于患者的职业史、典型临床表现和影像学发现，最初诊断为加速性矽肺，并经组织学证实。患者是肺移植的候选者。该病例表明，矽肺是一种罕见但在很大程度上可预防的疾病，对健康有严重影响且预后不良。
