Deslauriers Jean, Aubrée Nicolas, Shamji Farid M
Laval University, Quebec City, Quebec, Canada.
Centre Hospitalier Régional de Lanaudière, 1,000 Boulevard Ste-Anne, St-Charles Boromée, Quebec J6E-6J2, Canada.
Thorac Surg Clin. 2018 Aug;28(3):377-384. doi: 10.1016/j.thorsurg.2018.05.003.
Prosthetic airway reconstruction is seldom indicated in modern airway surgery because more than one-half the trachea can now be safely resected and the trachea be primarily reconstructed. In addition, an ideal prosthesis has yet to be developed with the use of those currently available being often associated with major morbidities and poor long-term outcomes. Recent developments in tracheal transplantation or tissue engineering strategies that promote and accelerate epithelial repair by controlling cell organization remains experimental, but showing great promise.
在现代气道手术中,很少需要进行人工气道重建,因为现在超过一半的气管可以安全切除并进行一期重建。此外,尚未开发出理想的假体,目前使用的假体常常伴有严重并发症且长期效果不佳。气管移植或组织工程策略方面的最新进展,即通过控制细胞组织来促进和加速上皮修复,仍处于实验阶段,但前景广阔。