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检测婴幼儿尿液中的巨细胞病毒抗原和抗体。

Detection of cytomegalovirus antigen and antibodies in the urine of small infants and children.

作者信息

Naqvi S H, Blair L L

出版信息

J Med Virol. 1986 Feb;18(2):139-47. doi: 10.1002/jmv.1890180206.

DOI:10.1002/jmv.1890180206
PMID:3005487
Abstract

The diagnostic efficacy of an enzyme immune assay to detect cytomegalovirus (CMV) antigen in the urine of infected infants and children was determined, and the effect that CMV-specific antibodies present in the urine have on the sensitivity of the test was ascertained. The antigen was detected in 84.4% of the CMV-culture-positive samples, while CMV-specific IgA was detected in 24% of CMV-culture-positive specimens. The absence of CMV-specific IgA correlated with detection of CMV antigen in the CMV-culture-positive urine specimens (p less than 0.05).

摘要

测定了酶免疫测定法检测受感染婴幼儿尿液中巨细胞病毒(CMV)抗原的诊断效力,并确定了尿液中存在的CMV特异性抗体对检测敏感性的影响。在84.4%的CMV培养阳性样本中检测到了抗原,而在24%的CMV培养阳性标本中检测到了CMV特异性IgA。在CMV培养阳性的尿液标本中,CMV特异性IgA的缺失与CMV抗原的检测相关(p小于0.05)。

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