The Human Performance Laboratory, Department of Exercise Science, Syracuse University, Syracuse, NY, 13244, USA.
Eur J Appl Physiol. 2018 Oct;118(10):2203-2211. doi: 10.1007/s00421-018-3948-2. Epub 2018 Jul 28.
While resistance exercise (RE) is known to be beneficial for overall health, one bout of RE acutely increases aortic stiffness and pulse pressure (PP). Increases in aortic stiffness and PP in a setting of aging has been shown to detrimentally impact cognitive function. This study examined whether increased aortic stiffness and PP from an acute bout of RE is associated with cognitive function.
Thirty-five participants (21 ± 2 years) underwent cognitive testing before and after either an acute bout of RE or a non-exercise time-control condition. Cognitive function was assessed as reaction time and accuracy during memory recognition, attention (Flanker) and working memory (N-back) tasks. Aortic stiffness and PP were measured via pulse wave velocity (PWV) and pulse wave analysis, respectively, using a brachial oscillometric device.
There were significant increases in aortic PWV and aortic PP following RE (p < 0.05) with no change in PWV or PP following the non-exercise control condition (p > 0.05). There was no change in accuracy metrics (% hits) across conditions for any cognitive task (p > 0.05). There was a condition-by-time interaction for reaction time for the memory task (p < 0.05) driven by a significant decrease in reaction times following RE (p < 0.05) with no change in reaction time following the non-exercise control (p > 0.05).
Functional increases in aortic stiffness and pulse pressure following acute RE occur in the absence of detrimental changes in cognitive function in young, healthy adults.
虽然阻力运动（RE）已知对整体健康有益，但一次 RE 会急性增加主动脉僵硬度和脉搏压（PP）。在衰老的情况下，主动脉僵硬度和 PP 的增加已被证明会对认知功能产生不利影响。本研究探讨了急性 RE 引起的主动脉僵硬度和 PP 增加是否与认知功能有关。
35 名参与者（21±2 岁）在进行急性 RE 或非运动时间对照条件前后接受认知测试。认知功能通过记忆识别、注意力（Flanker）和工作记忆（N-back）任务的反应时间和准确性进行评估。使用臂式振荡测量装置通过脉搏波速度（PWV）和脉搏波分析分别测量主动脉僵硬度和 PP。
RE 后主动脉 PWV 和主动脉 PP 显著增加（p<0.05），而非运动对照条件下 PWV 或 PP 无变化（p>0.05）。在任何认知任务中，准确性指标（%命中）在条件之间均无变化（p>0.05）。记忆任务的反应时间存在条件-时间交互作用（p<0.05），这是由 RE 后反应时间显著下降（p<0.05）引起的，而非运动对照条件下的反应时间没有变化（p>0.05）。
在年轻健康成年人中，急性 RE 后主动脉僵硬度和脉搏压的功能性增加不会导致认知功能的有害变化。
