Department of Neuroscience, Biomedicine and Movement Sciences, Section of Psychiatry,University of Verona,Verona,Italy.
Epidemiol Psychiatr Sci. 2019 Feb;28(1):18-20. doi: 10.1017/S2045796018000380. Epub 2018 Jul 30.
In individuals with coronary artery disease and concurrent depressive symptomatology, the evidence on the beneficial and harmful effects of antidepressants is very limited. Recently, a study was carried out to describe depressive symptoms and the treatments provided under real-world circumstances to cardiac patients who entered the Mayo Clinic cardiac rehabilitation program. Antidepressant use was associated with reductions in depressive symptoms, but also with poorer cardiovascular outcomes. In this commentary, the results of this study are discussed in view of their clinical implications for everyday clinical practice and for the production of knowledge.
在患有冠状动脉疾病和同时存在抑郁症状的个体中，关于抗抑郁药的益处和危害的证据非常有限。最近，一项研究旨在描述进入梅奥诊所心脏康复计划的心脏病患者的抑郁症状和实际情况下提供的治疗方法。抗抑郁药的使用与抑郁症状的减轻有关，但也与心血管结局恶化有关。在这篇评论中，将根据该研究结果对其临床意义进行讨论，以了解其对日常临床实践和知识产生的影响。
