Laboratório de Síntese Orgânica Limpa - LASOL, CCQFA - Universidade Federal de Pelotas - UFPel, P.O. Box 354, 96010-900 Pelotas, RS, Brazil.
Laboratório de Síntese Orgânica Limpa - LASOL, CCQFA - Universidade Federal de Pelotas - UFPel, P.O. Box 354, 96010-900 Pelotas, RS, Brazil.
Ultrason Sonochem. 2018 Dec;49:41-46. doi: 10.1016/j.ultsonch.2018.07.014. Epub 2018 Jul 17.
Herein, we described the ultrasound-assisted synthesis of thioesters via the Ag-catalyzed radical oxidative decarboxylation of α-keto acids, in the presence of disulfides. This protocol takes advantage of the sonication to prepare the title compounds in moderate to very good yields, in only 20 min of reaction. The positive effect of ultrasonic irradiation is attributed to both, the high mass transfer efficiency and to the induced radical formation in the reaction medium.
在此，我们描述了一种通过 Ag 催化的α-酮酸的自由基氧化脱羧反应，在二硫化物存在下合成硫酯的超声辅助方法。该方法利用超声辐射来制备标题化合物，反应仅需 20 分钟即可获得中等至非常好的产率。超声辐射的积极影响归因于高传质效率和反应介质中诱导的自由基形成。
