[病毒乳头瘤与恶性生殖器肿瘤]
[Virus papillomas and malignant genital tumors].
作者信息
Grussendorf-Conen E I
出版信息
Z Hautkr. 1985 Dec 15;60(24):1970-4.
PMID:3006372
Abstract
Morphological and epidemiological studies point to a close correlation between viral genital warts and genital cancer. Benign condylomata acuminata are commonly induced by HPV-6 and HPV-11. In precancerous bowenoid genital lesions, HPV-16 and HPV-18 could be cloned directly from cervical cancer tissue. Whereas the occurrence of HPV-6 and HPV-11 seems to be a low risk infection, HPV-16 and HPV-18 may represent a high risk for malignant conversion.
摘要
形态学和流行病学研究表明，病毒性尖锐湿疣与生殖器癌之间存在密切关联。良性尖锐湿疣通常由人乳头瘤病毒6型（HPV-6）和人乳头瘤病毒11型（HPV-11）引起。在癌前鲍温样生殖器病变中，HPV-16和HPV-18可直接从宫颈癌组织中克隆出来。虽然HPV-6和HPV-11的感染似乎风险较低，但HPV-16和HPV-18可能代表着恶性转化的高风险。
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