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一项针对新诊断脊柱转移瘤患者群体的全国性外科手术研究。

A Nationwide Study of Surgery in a Newly Diagnosed Spine Metastasis Population.

作者信息

Sohn Seil, Chung Chun Kee, Han Kyung Do, Jung Jin Hyung, Hyeun Joung Ho, Kim Jinhee, Chang Ung-Kyu, Sohn Moon Jun, Kim Sung Hwan

机构信息

Department of Neurosurgery, CHA Bundang Medical Center, CHA University College of Medicine, Seongnam, Korea.

Department of Neurosurgery, Seoul National University College of Medicine, Seoul, Korea.

出版信息

J Korean Neurosurg Soc. 2019 Jan;62(1):46-52. doi: 10.3340/jkns.2017.0304. Epub 2018 Aug 2.

Abstract

OBJECTIVE

The aim of this nationwide study was to analyze the current state of patients with newly diagnosed metastatic spine tumors according to surgical methods.

METHODS

Data was extracted from the Korean Health Insurance Review and Assessment Service database. Surgery was categorized into three.

METHODS

fusion, decompression, and vertebroplasty. Data included patient age, sex, health insurance type, and co-morbidities. Survival rates of metastatic spine tumor patients according to each surgical method were evaluated.

RESULTS

Among 1677 patients who had an operation, 823 patients were treated by fusion, 141 patients underwent decompression, and 713 patients were treated by vertebroplasty. The three most prevalent primary tumor sites were the lung, breast, and liver & biliary. On the other hand, the three most prevalent primary tumor sites of patients who underwent surgery were the lung, liver & biliary, and the prostate. The median survival periods for each surgical method in the metastatic spine tumor patients were 228 days for those who underwent surgery, 249 days for decompression, and 154 days for vertebroplasty. Age, sex, and comorbidities significantly affected survival rate.

CONCLUSION

For every primary tumor site, decompression was the least common surgical method during the study period. Although the three surgical methods did not significantly affect the survival period, patients with a poor prognosis tended to undergo vertebroplasty.

摘要

目的

这项全国性研究旨在根据手术方法分析新诊断的转移性脊柱肿瘤患者的现状。

方法

数据取自韩国健康保险审查与评估服务数据库。手术分为三类:融合术、减压术和椎体成形术。数据包括患者年龄、性别、健康保险类型和合并症。评估了根据每种手术方法的转移性脊柱肿瘤患者的生存率。

结果

在1677例接受手术的患者中,823例接受了融合术治疗,141例接受了减压术,713例接受了椎体成形术。三个最常见的原发肿瘤部位是肺、乳腺以及肝脏和胆道。另一方面,接受手术患者的三个最常见原发肿瘤部位是肺、肝脏和胆道以及前列腺。转移性脊柱肿瘤患者每种手术方法的中位生存期分别为:接受手术的患者为228天,减压术患者为249天,椎体成形术患者为154天。年龄、性别和合并症对生存率有显著影响。

结论

对于每个原发肿瘤部位,减压术是研究期间最不常见的手术方法。尽管这三种手术方法对生存期没有显著影响,但预后较差的患者倾向于接受椎体成形术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c29/6328801/a15cc879caf5/jkns-2017-0304f1.jpg

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