犬木糖醇中毒：最新进展

Xylitol Toxicosis in Dogs: An Update.

作者信息

Murphy Lisa A, Dunayer Eric K

机构信息

Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, PADLS New Bolton Center Toxicology Laboratory, 382 West Street Road, Kennett Square, PA 19348, USA.

Department of Veterinary Clinical Sciences, St. Matthew's University School of Veterinary Medicine, Grand Cayman, Cayman Islands; ASPCA Animal Poison Control Center, 1717 South Philo Road, Suite 36, Urbana, IL 61802, USA.

出版信息

Vet Clin North Am Small Anim Pract. 2018 Nov;48(6):985-990. doi: 10.1016/j.cvsm.2018.06.004. Epub 2018 Jul 29.

DOI:10.1016/j.cvsm.2018.06.004

PMID:30064708

Abstract

Xylitol ingestions in dogs may result in severe hypoglycemia followed by acute hepatic failure and associated coagulopathies. Aggressive treatment may be needed, but the prognosis is generally expected to be good for dogs developing uncomplicated hypoglycemia. Because of increased availability of xylitol-containing products in the market and in the dog's environment, it is likely that there will continue to be increased exposures and toxicity in dogs.

摘要

犬类摄入木糖醇可能会导致严重低血糖，随后引发急性肝衰竭及相关凝血功能障碍。可能需要积极治疗，但对于单纯发生低血糖的犬类，总体预后通常较好。由于市场上以及犬类生活环境中含木糖醇产品越来越多，犬类接触木糖醇并出现中毒反应的情况可能会持续增加。