Feller W F, Holt R, Spear S, Little J W
Am Surg. 1986 Mar;52(3):129-33.
The authors reviewed 100 consecutive patients with breast cancer treated by modified radical mastectomy and immediate breast reconstruction in order to assess the safety and efficacy of this procedure in terms of cancer control. The study began in 1978 and is continuing. The procedure involves a two-team approach with both the general surgeon and the plastic surgeon interviewing the patient preoperatively. Virtually all breast reconstruction involved the use of a submuscular silicone saline type of implant. The median follow-up is 36 months. Slightly over half of these cases were Stage 0 or Stage I. There have been eight recurrences, including five local or regional and three distant. No patient has died of her disease at this point. Cosmesis was equal to or superior to that seen in delayed breast reconstruction. There have been no hidden recurrences. Postoperative depression has been significantly less. We conclude that modified radical mastectomy with immediate breast reconstruction is a safe and effective alternative to modified radical mastectomy alone.
作者回顾了100例连续接受改良根治性乳房切除术及即刻乳房重建术治疗的乳腺癌患者,以评估该手术在癌症控制方面的安全性和有效性。该研究始于1978年,仍在继续。手术采用双团队方式,普通外科医生和整形外科医生在术前均对患者进行问诊。几乎所有乳房重建都使用了胸肌下硅凝胶盐水型植入物。中位随访时间为36个月。这些病例中略超过一半为0期或I期。出现了8例复发,包括5例局部或区域复发和3例远处复发。目前尚无患者死于该疾病。美容效果等同于或优于延迟乳房重建。未出现隐匿性复发。术后抑郁明显减轻。我们得出结论,改良根治性乳房切除术联合即刻乳房重建术是单纯改良根治性乳房切除术的一种安全有效的替代方案。