Lim Jason Beng Teck, Soeharno Henry, Tan Mann Hong
Department of Orthopaedic Surgery, Singapore General Hospital, Outram Road, Singapore, 169608, Republic of Singapore.
Eur J Orthop Surg Traumatol. 2019 Jan;29(1):9-15. doi: 10.1007/s00590-018-2284-x. Epub 2018 Jul 31.
Sacral chordoma are rare low-to-intermediate grade malignant tumours that occur most commonly within the sacrum. Sacrectomy with wide resection margins seems to offer the best long-term prognosis. This study aims to review the management of sacral chordomas including the duration of symptoms, features, treatment, complications and local recurrence rate following surgery at a tertiary centre. We retrospectively reviewed 11 patients treated at our institution between years 1999 and 2015. Patient data included age, sex, history, radiographs, surgical details, onset of recurrence, subsequent treatment, disease-free survival and overall survival were analyzed. Nine patients underwent surgical management with 1 through a sacral approach and eight patients through a combined abdominosacral approach. Despite wide resection in our series, sacral chordoma poses a major problem with approximately 60% of patients having local recurrence in their follow-up.
骶骨脊索瘤是罕见的低至中等分级的恶性肿瘤，最常发生于骶骨。手术切缘广泛的骶骨切除术似乎能带来最佳的长期预后。本研究旨在回顾一家三级医疗中心对骶骨脊索瘤的治疗情况，包括症状持续时间、特征、治疗、并发症以及术后局部复发率。我们回顾性分析了1999年至2015年间在我院接受治疗的11例患者。分析了患者的年龄、性别、病史、X光片、手术细节、复发时间、后续治疗、无病生存期和总生存期等数据。9例患者接受了手术治疗，其中1例采用经骶骨入路，8例采用经腹骶联合入路。尽管在我们的研究系列中手术切缘广泛，但骶骨脊索瘤仍是一个重大问题，约60%的患者在随访中出现局部复发。
