Mohanakkannan S, Perumal Sowmini R, Velayudham Sakthi, Jeyaraj K Malcolm, Arunan S
Department of Neurology, Stanley Medical College and Hospital, Chennai, Tamil Nadu, India.
J Neurosci Rural Pract. 2018 Jul-Sep;9(3):431-433. doi: 10.4103/jnrp.jnrp_555_17.
Morvan's syndrome is an autoimmune disorder of peripheral and central nervous system mediated by VGKC antibody. Here we report a case of Morvans syndrome who presented 1 month after ayurvedic drug intake. She presented with symptoms of peripheral nerve hyperexcitablity and autoimmune testing revealed positive result for VGKC antibody. Heavy metals level was also significantly raised. She improved after a course of steroids. This case report tries to highlight the association of VGKC mediated Morvans syndrome with heavy metal poisoning and its incidental occurence after Ayurvedic drug intake.
莫旺综合征是一种由电压门控钾通道(VGKC)抗体介导的外周和中枢神经系统自身免疫性疾病。在此,我们报告一例在服用阿育吠陀药物1个月后出现的莫旺综合征病例。她表现出外周神经兴奋性增高的症状,自身免疫检测显示VGKC抗体呈阳性。重金属水平也显著升高。经过一个疗程的类固醇治疗后,她的病情有所改善。本病例报告旨在强调VGKC介导的莫旺综合征与重金属中毒的关联以及服用阿育吠陀药物后该病的偶发情况。