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韩国的Dupuytren 氏病流行病学:一项全国性基于人群的研究。

The Epidemiology of Dupuytren's Disease in Korea: a Nationwide Population-based Study.

机构信息

Department of Orthopaedic Surgery, Hanyang University College of Medicine, Seoul, Korea.

Department of Orthopaedic Surgery, Myongji Hospital, Goyang, Korea.

出版信息

J Korean Med Sci. 2018 Jun 18;33(31):e204. doi: 10.3346/jkms.2018.33.e204. eCollection 2018 Jul 30.

Abstract

BACKGROUND

To date, there have been few reports on the nationwide population-based epidemiology of Dupuytren's disease (DD). We investigated the prevalence and incidence of DD in Korea using the large dataset provided by the Korean Health Insurance Review and Assessment Service. This study is the second nationwide epidemiological study of DD after the study in Taiwan.

METHODS

Records of patients diagnosed with DD between 2007 and 2014 were extracted from the large dataset by diagnostic code searching (International Classification of Disease 10th revision code M72.0) and were included in the study. We calculated the prevalence and incidence of DD based on the total population of Korea provided by the Korean Statistical Information Service. Diseases associated with DD and the trends in surgery for DD were also analyzed.

RESULTS

A total 16,630 patients were diagnosed with DD during the study period. The mean annual prevalence was 32.2 per 100,000 population (41.8 per 100,000 for men; 22.5 per 100,000 for women). The mean annual incidence was 1.09 per 100,000 population (1.80 per 100,000 for men; 0.38 per 100,000 for women). The common diseases associated with DD were hypertension (30.5%), diabetes mellitus (26.7%), hyperlipidemia (20.4%), ischemic heart disease (7.9%), and cerebrovascular disease (4.6%). The mean annual proportion of the patients who had surgery for DD was 5.24% of all DD patients.

CONCLUSION

The prevalence and incidence of DD in Korea were 100-1,000 times lower than those in western countries; however, it was slightly larger than that in Taiwan.

摘要

背景

迄今为止,有关全国范围内的掌腱膜挛缩症(Dupuytren's disease,DD)的流行病学研究报告较少。我们使用韩国健康保险审查和评估服务(Korean Health Insurance Review and Assessment Service)提供的大型数据集,对韩国的 DD 患病率和发病率进行了调查。这项研究是继台湾之后的第二次全国性 DD 流行病学研究。

方法

通过诊断代码搜索(国际疾病分类第 10 版代码 M72.0)从大型数据集中提取了 2007 年至 2014 年间被诊断为 DD 的患者记录,并将其纳入研究。我们根据韩国统计信息服务局(Korean Statistical Information Service)提供的韩国总人口计算了 DD 的患病率和发病率。还分析了与 DD 相关的疾病以及 DD 手术的趋势。

结果

在研究期间,共有 16630 名患者被诊断为 DD。平均年患病率为每 10 万人 32.2 例(男性为每 10 万人 41.8 例;女性为每 10 万人 22.5 例)。平均年发病率为每 10 万人 1.09 例(男性为每 10 万人 1.80 例;女性为每 10 万人 0.38 例)。与 DD 相关的常见疾病有高血压(30.5%)、糖尿病(26.7%)、高血脂(20.4%)、缺血性心脏病(7.9%)和脑血管疾病(4.6%)。每年接受 DD 手术的患者比例平均为所有 DD 患者的 5.24%。

结论

韩国的 DD 患病率和发病率是西方国家的 100-1000 倍;但略高于台湾。

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