副肿瘤神经系统综合征。
Paraneoplastic Neurologic Syndromes.
机构信息
Neuroimmunology, Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Casanova 143, Barcelona, Spain 08036; Neurology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19107, USA.
Neurology, Hospital Clínic and Neuroimmunology, Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Casanova 143, Barcelona, Spain 08036; University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19107, USA.
出版信息
Neurol Clin. 2018 Aug;36(3):675-685. doi: 10.1016/j.ncl.2018.04.015. Epub 2018 Jun 18.
Paraneoplastic neurologic syndromes (PNS) are mostly immune-mediated disorders that occur in patients with cancer. Because the same neurologic syndromes may occur without a cancer association it is important to know the likelihood of PNS, which is based in part on the syndrome and the patient's demographics and risk factors for cancer. The presence of specific antineuronal antibodies can facilitate the diagnosis and suggest treatment strategies. Although some PNS are rarely responsive to therapies, other disorders are highly treatment responsive.
副肿瘤性神经系统综合征（PNS）大多是免疫介导的疾病，发生在癌症患者中。由于相同的神经系统综合征可能在没有癌症关联的情况下出现，因此了解 PNS 的可能性非常重要，这部分基于综合征以及患者的人口统计学和癌症风险因素。特定的抗神经元抗体的存在可以促进诊断并提示治疗策略。虽然一些 PNS 对治疗很少有反应，但其他疾病对治疗高度敏感。
Zotero 插件