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血疱样动脉瘤破裂后的自发愈合

Spontaneous Healing of a Ruptured Blood Blister-Like Aneurysm.

作者信息

Zeineddine Hussein A, Jones Wesley, Conner Christopher R, Simpson Brett, Blackburn Spiros, Day Arthur L

机构信息

Department of Neurological Surgery, The University of Texas Health Science Center at Houston, Houston, Texas, USA.

Department of Neurological Surgery, The University of Texas Health Science Center at Houston, Houston, Texas, USA.

出版信息

World Neurosurg. 2018 Nov;119:85-88. doi: 10.1016/j.wneu.2018.07.202. Epub 2018 Aug 1.

Abstract

BACKGROUND

Blood blister-like aneurysms (BBAs) are an uncommon group of arterial aneurysms with a high risk of rupture, progression, and repeat rupture. The best intervention is unclear; however, their clinical behavior typically requires urgent intervention. We describe a BBA managed conservatively with complete resolution found at follow-up.

CASE DESCRIPTION

A 50-year-old woman presented with a Hunt-Hess grade 2, Fisher grade 3 subarachnoid hemorrhage (SAH). Computed tomography (CT) revealed mild hydrocephalus with a thick basal SAH that was eccentric to the left. The findings from CT angiography were negative. Digital subtraction arteriography (DSA) revealed a focal protuberance along the dorsal surface of the left ophthalmic segment that was concerning for a dorsal variant BBA. Repeat angiography 48 hours later demonstrated receding of the ectasia, with replacement by a <1-mm defect resembling a dorsal vessel surface fenestration. DSA 7 days after her presentation showed further healing. At 6 weeks, DSA showed no residual abnormality.

CONCLUSIONS

DSA remains an important imaging study for the detection of small aneurysms, because CT angiography might not have sufficient resolution. Our unique case provides strong evidence that BBAs represent a parent artery focal dissection. BBAs can remodel over time, usually with enlargement and repeat rupture if untreated. It is possible, as we have demonstrated, that some small lesions presenting with SAH might spontaneously heal without intervention.

摘要

背景

血泡样动脉瘤(BBAs)是一组少见的动脉瘤,具有破裂、进展和再次破裂的高风险。最佳干预措施尚不清楚;然而,其临床行为通常需要紧急干预。我们描述了一例通过保守治疗后在随访中完全消退的血泡样动脉瘤。

病例描述

一名50岁女性,Hunt-Hess分级为2级,Fisher分级为3级蛛网膜下腔出血(SAH)。计算机断层扫描(CT)显示轻度脑积水,基底SAH较厚且偏向左侧。CT血管造影结果为阴性。数字减影血管造影(DSA)显示左侧眼动脉段背侧表面有一个局灶性隆起,怀疑为背侧变异型血泡样动脉瘤。48小时后复查血管造影显示扩张消退,代之以一个<1mm的缺损,类似背侧血管表面开窗。发病7天后的DSA显示进一步愈合。6周时,DSA显示无残留异常。

结论

DSA仍然是检测小动脉瘤的重要影像学检查,因为CT血管造影可能没有足够的分辨率。我们的独特病例提供了有力证据,表明血泡样动脉瘤代表母动脉局灶性夹层。血泡样动脉瘤可随时间重塑,通常如果不治疗会扩大并再次破裂。正如我们所证明的,一些伴有SAH的小病变有可能在未经干预的情况下自发愈合。

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