Chen Zhengyan, Dai Na, Lin Sheng, Zhou Guangli
J Perianesth Nurs. 2018 Aug;33(4):448-452. doi: 10.1016/j.jopan.2016.07.009. Epub 2017 Apr 27.
To evaluate the impact of dexmedetomidine (DEX) on intraoperative wake-up tests.
American Society of Anesthesiologists category I or II patients were divided into two groups: a propofol-remifentanil group (group R, n = 20) and a DEX-propofol-remifentanil group (group D, n = 20).
The patients in group D received DEX, whereas the patients in group R received the same volume of saline. The other anesthetic methods and drugs (propofol and remifentanil) were the same in both groups. During the wake-up test, patients were repeatedly asked to move their fingers.
All the wake-up tests were successfully performed. There was no significant difference in the mean wake-up time between the two groups. Eighteen patients exhibited better wake-up quality in group D as did eight patients in group R. The patients in group D had a significantly better overall wake-up quality than those in group R (P <.05).
DEX did not affect the wake-up time and increased the wake-up quality.
评估右美托咪定（DEX）对术中唤醒试验的影响。
美国麻醉医师协会I或II级患者分为两组：丙泊酚-瑞芬太尼组（R组，n = 20）和DEX-丙泊酚-瑞芬太尼组（D组，n = 20）。
D组患者接受DEX，而R组患者接受相同体积的生理盐水。两组的其他麻醉方法和药物（丙泊酚和瑞芬太尼）相同。在唤醒试验期间，反复要求患者移动手指。
所有唤醒试验均成功完成。两组之间的平均唤醒时间无显著差异。D组有18例患者唤醒质量较好，R组有8例患者唤醒质量较好。D组患者的总体唤醒质量明显优于R组（P <.05）。
DEX不影响唤醒时间，并提高了唤醒质量。
