Sidibé Sidikiba, Delamou Alexandre, Kaba Mohamed Lamine, Magassouba Aboubacar Sidiki, Samake Amara Tabaouo, Dongo Yao Serge Arthur, Kadio Kadio Jean-Jacques Olivier, Dimio Sandouno Sah, Camara Lansana Mady, Babalola Stella
National Center for Training and Rural Health Research, Maferinyah, Guinea.
Faculty of Medicine, Pharmacy and Odonto-Stomatology, Gamal Abdel Nasser University, Conakry, Guinea.
J Public Health Afr. 2018 May 21;9(1):708. doi: 10.4081/jphia.2018.708.
Whereas the HIV prevalence in Guinea is among the lowest in Africa, many PLHIV in Guinea are malnourished. This study assessed the effect of a nutritional supplementation program on body mass index and CD4 count among adult PLHIV on ART. Study participants were PLHIV who came for consultation in the study sites between May and July 2016. The data came from two sources: retrospectively from participants' medical records and interviews at the time of recruitment into the study. About six months before they were recruited into the study, some of the PLHIV started to receive a monthly nutritional supplementation consisting of Corn-Soy Blend and oil. Analytic methods included bivariate and multivariable methods. The intervention increased the mean BMI by 7.4% and the average current CD4 count by 4.7% compared to nonintervention (P<0.001). Programs in low resource settings should consider nutrition assistance as part of a comprehensive strategy to ensure optimal metabolic and immunological functions among PLHIV.
尽管几内亚的艾滋病毒流行率在非洲处于最低水平，但几内亚的许多艾滋病毒感染者都营养不良。本研究评估了营养补充计划对接受抗逆转录病毒治疗的成年艾滋病毒感染者体重指数和CD4细胞计数的影响。研究参与者是2016年5月至7月期间在研究地点前来咨询的艾滋病毒感染者。数据来自两个来源：回顾性地从参与者的病历以及招募进入研究时的访谈中获取。在被招募进入研究前约六个月，一些艾滋病毒感染者开始每月接受由玉米-大豆混合粉和油组成的营养补充。分析方法包括双变量和多变量方法。与未干预组相比，干预使平均体重指数提高了7.4%，当前平均CD4细胞计数提高了4.7%（P<0.001）。资源匮乏地区的项目应将营养援助视为确保艾滋病毒感染者实现最佳代谢和免疫功能的综合战略的一部分。
