Sekiryu Tetsuju, Shintake Hiroaki, Kasai Akihito, Ojima Akira
Nippon Ganka Gakkai Zasshi. 2016 Dec;120(12):837-45.
Background: Acute annular retinopathy (AAOR) is a rare entity showing grayish spots with annular lesions. We report the clinical characteristics of a patient with AAOR derived by using multimodal imaging including spectral-domain optical coherence tomography (OCT), fundus autofluorescence (FAF), and an adaptive optics fundus camera. Case: A 56-year-old man who had fever one month and a half before presenting. He noticed bilateral visual loss after lowering of fever. Clinical findings: Grayish white rings of different sizes were seen in the posterior fundus. Margin of the lesion showed hyperautofluorescence. OCT demonstrated an indistinct ellipsoid zone, disruption of external limiting membrane, and bulging of the retinal pigment epithelium in the annular lesions. We found hyperreflective foci in the inner retina and an indistinct interdigitation zone on the OCT images and indistinct cone mosaic patterns on the AO images at an ophthalmoscopically normal fovea in the left eye. Conclusion: Multimodal imaging showed the damage in the photoreceptors and the retinal pigment epithelium at the annular lesions. OCT and AO imaging can demonstrate abnormal findings in ophthalmoscopically normal areas in eyes with AAOR.
急性环形视网膜病变(AAOR)是一种罕见的疾病,表现为带有环形病变的灰白色斑点。我们报告了一例通过使用包括光谱域光学相干断层扫描(OCT)、眼底自发荧光(FAF)和自适应光学眼底相机在内的多模态成像得出的AAOR患者的临床特征。病例:一名56岁男性,在就诊前一个半月曾发烧。退烧后他注意到双眼视力下降。临床发现:眼底后部可见不同大小的灰白色环。病变边缘显示高自发荧光。OCT显示环形病变处椭圆体带不清晰、外界膜破坏以及视网膜色素上皮隆起。我们在左眼检眼镜检查正常的黄斑中心凹的OCT图像上发现视网膜内层有高反射灶和不清晰的指状交叉带,在AO图像上发现不清晰的视锥细胞镶嵌图案。结论:多模态成像显示环形病变处光感受器和视网膜色素上皮受损。OCT和AO成像可以在AAOR患者检眼镜检查正常的区域显示异常发现。